In this episode, I am joined by Dr Antonio Scalfari,consultant Neurologist at the tertiary centre for the management of MS and neuro-inflammatory diseases (Imperial College Healthcare Trust; Charing Cross and St Mary Hospitals) and at the neurology department of Northwest London Healthcare Trust. He also runs his private Neurology practice in London.

He is an Honorary Senior Clinical Lecturer at Imperial College London, where he contributes to the teaching activities for medical students. His main research interest is in Multiple Sclerosis epidemiology and prognostic factors. He has authored several scientific articles in highly impact journals and he also participates often as a speaker at international conferences and webinars and seminars in MS. He continues his research activity in collaboration with other international academic orgnisations.

Antonio is one of the first Neurologists in the world who has dedicated his time researching the prognostic factors of progression in MS and he discovering that the process of natural progression of MS as independent of the MS relapses, there is something more that drives the natural ms progression, and he introduced the concept of smouldering MS and we will talk about this later, he is also investigating the impact of ageing process on MS brain health.


In this interview we discuss mechanisms of aging and what can we all do to slow and reverse aging process. This episode includes of basic science, actionable protocols, right down to the details of what to do, by the end you will have knowledge of the biology of aging and how to offset it.
Episode recording timeline:

00:00- 2:44 min Intro of the whole episode and Dr Scalfari Bio

2: 44 min What does the brain health mean to Dr Scalfari and his family

4:40 min Is ageing a disease and can we bio- hack the aging process?

6:45 min What Mediterranean people do to expand their life longevity?

7:40 min Does the longevity gene exist?

8:12 min Are people with MS are born to have or acquired to have MS?

10:06 min Discussion about Sarcopenia( Low muscle mass that happens with ageing process) and evidence of grip strengh( potential biomarker of aging) and Uric acid antioxidant

14:48 min: what is the peak age of of developing MS disease

20:49: min How MS brain age?

24: 20 min How to modify natural ageing process living with MS

26:43 min Immunosenesence- ageing of immune and brain cells

28:24 min Remyelination process of the central nervous system

29:49 min When people with MS age do they have less MS disease activity?

32:59 min Smouldering MS concept, what is it and why it is important ?

46:25 min Intermittent fasting protocols