US equity markets retreated amid fresh weakness for a number of large capitalisation technology companies and as the rally among small capitalisation stocks stalled - Dow dropped -533-points or -1.29%, having logged consecutive record closing highs. Investment banks Goldman Sachs Group Inc and JPMorgan Chase & Co both fell -3.18% to be the worst performers in the 30-stock index overnight. Amazon.com Inc (down -2.22%) and Apple Inc (-2.05%) both fell over >2%.

The broader S&P500 fell -0.78% Healthcare (down -2.29%) leading ten of the eleven primary sectors lower. Energy (up +0.33%) was the only primary sector to advance overnight. Eli Lilly & Co fell -6.26%, extending the previous session’s -3.8% decline amid concerns about intensifying competition among obesity-drug developers. Swiss pharmaceutical company Roche Holding AG announced positive early-stage trial data for its experimental obesity pill a day earlier. Ozempic manufacturer Novo Nordisk A/S fell -3.48%., taking its two-day slide to almost 9%.