ALS Untangled Series: Ep. 34 - Ursodiol
Aug 22, 2020 ·
14m 1s
![ALS Untangled Series: Ep. 34 - Ursodiol](https://d3wo5wojvuv7l.cloudfront.net/t_square_limited_480/images.spreaker.com/original/304f436c9370c5ce5056406549ff413e.jpg)
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Description
Ursodiol or ursodeoxycholic acid (UDCA) is a bile acid derivative of cholesterol. Since it can have antioxidant, anti-inflammatory and anti-apoptotic effects, it has mechanisms by which it could slow ALS...
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Ursodiol or ursodeoxycholic acid (UDCA) is a bile acid derivative of cholesterol. Since it can have antioxidant, anti-inflammatory and anti-apoptotic effects, it has mechanisms by which it could slow ALS progression. Here we discuss trials of UDCA in PALS, including the taurine-conjugated form (TUDCA). Some of these trials came out after our ALSUntangled review, and have changed our opinion about UDCA as an ALS treatment.
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Information
Author | CReATe Consortium |
Organization | CReATe Consortium |
Website | - |
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